It really seems like an unavoidable storyline given the ages of the characters, the fact that many of them are in long-term relationships and their personalities. I mean Derek already explicitly said to Meredith prior to their post-it wedding that he wanted children and presumably happy, whole Meredith who finally took the plunge with him wants to have his babies too. She also can't possibly expect us to believe that Izzie, Lexie and a fucking pediatric surgeon (Arizona) wouldn't want kids. We also know Callie wants children since she was planning on having a baby with George prior to Gizziegate and she discussed children with her father two weeks ago. Not that Grey's is particularly realistic it would be totally stupid if this show continued to go on for even a few more years and not one of the couples had or adopted or even discussed a child.

Frankly though I'm not all that surprised by Shonda though given what she's done with Addison on Private Practice. Addison, the neo-natal surgeon who loves babies and went to LA b/c she wanted a baby (and subsequently was told it wasn't likely going to happen naturally) has essentially given up on her desperate desire to have a child. I mean the storyline has just poof gone. It's completely unrealistic for Addison to desperately want a child and then have that desire completely ignored for years, again she's not getting any younger.